despair

Noun

• the feeling that everything is wrong and nothing will turn out well
  • they moaned in despair and dismay
    
  • one harsh word would send her into the depths of despair
    

• a state in which all hope is lost or absent
  • in the depths of despair
    
  • they were rescued from despair at the last minute
    
  • courage born of desperation
    

Verb

• abandon hope; give up hope; lose heart
  • Don't despair--help is on the way!